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Record W4240413671 · doi:10.32920/ryerson.14645043.v1

Fatigue in chronic hepatitis C infection a mixed method study

2021· preprint· en· W4240413671 on OpenAlexaff
Dora Marta Zalai

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldMedicine
TopicHepatitis C virus research
Canadian institutionsToronto Metropolitan UniversitySystems, Applications & Products in Data Processing (Canada)
Fundersnot available
KeywordsMedicineChronic fatigue syndromeChronic fatigueInsomniaChronic hepatitisCognitionPhysical therapyClinical psychologyInternal medicinePsychiatryImmunology

Abstract

fetched live from OpenAlex

Fatigue is a main patient reported outcome of chronic hepatitis C (HCV) infection; yet its contributors are unknown. Objectives: The study (1) evaluated fatigue predictors, (2) tested the mediating role of fatigue cognitions, (3) screened for sleep disorders, and (4) explored fatigue from patients’ perspectives. Participants: Both sexes (age>18 years, N = 115) with chronic HCV infection. Design: Cross-sectional. Results: Sixty percent reported severe fatigue (FSS≥4). Fatigue perceptions were the main predictors of fatigue (ß=.58, bias corrected CI = .070-.163). Fatigue perceptions mediated the relationship between comorbidities and fatigue. Half of the sample reported clinically significant symptoms of insomnia and/or sleep apnea. Eight main fatigue themes were endorsed by the participants. Conclusions: Fatigue and sleep disorders were clinically significant issues. Fatigue cognitions may contribute to severe fatigue outcomes. Significance: Integrating the findings into existing sleep and fatigue treatments could improve clinical outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.038

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.006
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.113
GPT teacher head0.452
Teacher spread0.339 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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