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Record W4243371481 · doi:10.1016/j.imu.2019.100227

CBIR system using Capsule Networks and 3D CNN for Alzheimer's disease diagnosis

2019· article· en· W4243371481 on OpenAlexfundno aff
K.R. Kruthika, Rajeswari, H. D. Maheshappa

Bibliographic record

VenueInformatics in Medicine Unlocked · 2019
Typearticle
Languageen
FieldComputer Science
TopicAI in cancer detection
Canadian institutionsnot available
FundersJohnson and Johnson Pharmaceutical Research and DevelopmentNational Institute on AgingNational Institute of Biomedical Imaging and BioengineeringCanadian Institutes of Health ResearchGenentechNational Institutes of HealthH. Lundbeck A/SServierEisaiNorthern California Institute for Research and EducationDoD Alzheimer's Disease Neuroimaging InitiativePfizerBiogenBioClinicaTakeda Pharmaceutical CompanyJanssen Alzheimer Immunotherapy Research And DevelopmentAbbVieRocheUniversity of Southern CaliforniaNovartis Pharmaceuticals CorporationU.S. Department of DefenseEli Lilly and CompanyBristol-Myers SquibbAlzheimer's Drug Discovery FoundationMerckFujirebio EuropeAlzheimer's AssociationFoundation for the National Institutes of HealthGE HealthcareAlzheimer's Disease Neuroimaging Initiative
KeywordsAutoencoderComputer scienceConvolutional neural networkArtificial intelligenceDeep learningPattern recognition (psychology)Image retrievalFeature extractionContent-based image retrievalImage (mathematics)

Abstract

fetched live from OpenAlex

Alzheimer’s disease (AD) is an irreversible disorder of the brain related to loss of memory, commonly seen in the elderly and aging population. Implementation of revolutionary computer aided diagnosis techniques with Content Based Image Retrieval (CBIR) has created new potentials in Magnetic resonance imaging (MRI) in relevant image retrieval and training for detection of progression of AD in early stages. This paper proposed a CBIR system using 3D Capsule Network, 3D-Convolutional Neural Network and pre-trained 3D-autoencoder technology for early detection of Alzheimer's. A 3D-Capsule Networks (CapsNets) is capable of fast learning, even for small datasets and can effectively handle robust image rotations and transitions. It was observed that an ensemble method using 3D-CapsNets and a convolutional neural network (CNN) with 3D-autoencoder, increased the detection performance comparing to Deep-CNN alone. CBIR using the proposed model was found to be up to 98.42% accurate in AD classification. CapsNet is a promising new technique for image classification, and further experiments using more robust computation resources and refined CapsNet architectures may produce better outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.015
Threshold uncertainty score0.030

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.277
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations18
Published2019
Admission routes1
Has abstractyes

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