PERTUSSIS IS A FREQUENT CAUSE OF PROLONGED COUGH ILLNESS IN ADULTS AND ADOLESCENTS
Bibliographic record
Abstract
PERTUSSIS IS A FREQUENT CAUSE OF PROLONGED COUGH ILLNESS IN ADULTS AND ADOLESCENTS [Senzilet LD, et al.Clin Infect Dis2001;32:1691]: This is a report from the Sentinel Health Unit Surveillance System, which is a network of nine health units located in eight Canadian provenances with approximately 2.8 million residents. The study examined the frequency of pertussis infection in 422 adults and adolescents >12 years with a coughrelated illness that persisted 7–56 days. Of these, 88 patients (20%) had laboratory-confirmed pertussis or laboratory evidence of this infection. Those with positive laboratory tests had a longer duration of cough (mean of 56 days) and more had vomiting associated with cough (46%). The authors concluded that pertussis is a common cause of prolonged cough illness in adolescents and adults. Comment. The average age in this study was 41.3 years, 90% had what was described as a “violent cough,” and about 50% had a history of pertussis vaccination. There are now several reports that indicate that 10%–20% of adults with a prolonged cough illness have evidence of pertussis. One of the major limitations in all of the studies is the difficulty of establishing this diagnosis with currently available laboratory techniques. Of particular interest in this report is the editorial comment by Kathryn Edwards from Vanderbilt concerning acellular vaccines. She reports that the NIH has completed a trial with this vaccine in adolescents and adults and the results are currently being analyzed. She predicts that booster immunization of adolescents will be found to be cost effective and will be implemented in the United States as it has already in France, Canada, and Germany. The decision about the adult boosters is unclear.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.019 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".