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Vitamin B12

2007· article· en· W4244470690 on OpenAlexaboutno aff
A. Stewart Truswell

Bibliographic record

VenueNutrition & Dietetics · 2007
Typearticle
Languageen
FieldMedicine
TopicFolate and B Vitamins Research
Canadian institutionsnot available
Fundersnot available
KeywordsVitamin B12Subclinical infectionMedicineVitaminDietary Reference IntakeCobalaminEnvironmental healthVitamin deficiencyFortified FoodPhysiologyFood scienceNutrientEndocrinologyBiologyInternal medicine

Abstract

fetched live from OpenAlex

KEY POINTS• Subclinical vitamin B12 deficiency (low serum vitamin B12, and/or raised methylmalonate) occurs in 10% or more of older people, in Australia and other developed countries.Causes include inadequate liberation of vitamin B12 from its natural binding to the protein in foods because of poor gastric acid production.There is evidence that in some cases, the diet has been inadequate in animal foods.At present, it is not clear whether these low biochemical values lead to any serious consequences.• The recent recommended dietary allowance reports for vitamin B12 in the USA and Canada recommend that older people should obtain most of their vitamin B12 from fortified foods or from supplements of free (crystalline) vitamin B12.In Australia and New Zealand, advice in the Nutrient Reference Values report is that older people with low stomach acid secretion 'May require higher intakes of vitamin B12 rich foods "(e.g.meat)" vitamin B12 fortified foods "(not generally available here)" or supplements'.• Dietary deficiency of vitamin B12 occurs in strict vegans.It is usually subclinical.But very severe clinical deficiency has been reported in infants breastfed by a vegan mother.• Now that folate intakes have been increased by fortification of foods-mandatory in North America, at present voluntary in Australia and New Zealand-some experts and some evidence warn that it may be advisable for people to increase B12 intake.• Meat and meat products are the major source of vitamin B12 in Britain.Presumably this would be similar in Australia.Liver and kidney are the foods richest in this vitamin.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.068
Threshold uncertainty score0.229

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0010.000
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0680.035

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.337
Teacher spread0.308 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations24
Published2007
Admission routes1
Has abstractyes

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