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Record W4245579290 · doi:10.21203/rs.3.rs-28495/v1

Brain Connectivity and Behaviour in Post-Concussion Syndrome: A Scoping Review Protocol

2020· review· en· W4245579290 on OpenAlexafffund
Melisa Gumus, Alexandra Santos, Maria Carmela Tartaglia

Bibliographic record

VenueResearch Square (Research Square) · 2020
Typereview
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsUniversity of Toronto
FundersUniversity of Toronto
KeywordsDiffusion MRIConcussionNeuroimagingWhite matterProtocol (science)Functional connectivityPsychologyPhysical medicine and rehabilitationTraumatic brain injuryCognitionMedicinePost-concussion syndromeNeuroscienceMagnetic resonance imagingPsychiatryPoison controlPathologyRadiologyInjury preventionMedical emergency

Abstract

fetched live from OpenAlex

Abstract Background About 10-15% of patients experience persistent symptoms 3-months post-concussion, referred to as Post-Concussion Syndrome (PCS). There are no biomarkers for detecting this condition, but advanced neuroimaging tools such as Diffusion Tensor/Weighted Imaging (DTI/DWI) or functional MRI (fMRI) can detect subtle changes in the integrity of white matter tracts or brain activity, respectively. Methods This study protocol presents search strategies for a scoping review that provides an overview of the studies that assessed both alterations of structural and/or functional connectivity and cognitive/neuropsychiatric outcomes in PCS. Discussion A better understanding of the brain-behaviour relationships in PCS can lead to improved diagnosis of this condition. Scoping Review Protocol Registration: osf.io/sqt7d

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.044
metaresearch head score (Gemma)0.061
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.078
Threshold uncertainty score0.260

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0440.061
Meta-epidemiology (narrow)0.0040.003
Meta-epidemiology (broad)0.0090.009
Bibliometrics0.0160.014
Science and technology studies0.0030.003
Scholarly communication0.0060.005
Open science0.0040.005
Research integrity0.0080.004
Insufficient payload (model declined to judge)0.0780.012

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.242
GPT teacher head0.556
Teacher spread0.315 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2020
Admission routes2
Has abstractyes

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