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Record W4245797062 · doi:10.1002/pep2.24152

Issue Information

2020· paratext· en· W4245797062 on OpenAlexaff
Fred Naider, Robin E. Offord, Sheena E. Radford, Ronald T. Raines, Tomi K. Sawyer, Peter W. Schiller, John A. Smith, Dhrubajyoti Datta, Saibal Jana, Om Shanker Tiwari, Andrew R. Urmey, Neal J. Zondlo, Takahiro Takekiyo, Natsuki Yamada, Taku Amo, Yukihiro Yoshimura

Bibliographic record

VenuePeptide Science · 2020
Typeparatext
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBiotin and Related Studies
Canadian institutionsMontreal Clinical Research Institute
Fundersnot available
KeywordsCitationComputer scienceInformation retrievalWorld Wide Web

Abstract

fetched live from OpenAlex

The aggregation behaviour of peptide fragments of proteins in aqueous solutions with ionic liquids (ILs) could help identify the relationship between IL-protein interactions and structural behaviour of intrinsically disordered proteins in this media. Takekiyo et al. report that the addition of 1-butyl-3methylimidazolium thiocyanate, but not ethylammonium nitrate, to amyloid 1-11 peptide (A 1-11 ) leads to the formation of intermolecular -sheet structure (aggregation). Cationic species are associated with the ability to mask the charged residues of A 1-11 , whereas anionic species depend on the aggregation selectivity of A 1-11 . The results could help develop new antiamyloidogenic agents and alternative solvents for stable protein biomaterials. (doi: 10.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.101
Threshold uncertainty score0.144

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.007
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0010.000
Scholarly communication0.0040.003
Open science0.0020.002
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.8990.779

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.256
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

Explore more

Same venuePeptide ScienceSame topicBiotin and Related StudiesFrench-language works237,207