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Record W4246112699 · doi:10.1002/9780470054581.eib128

Biophotoreceptor Arrays

2010· other· en· W4246112699 on OpenAlexaff
George K. Knopf, Wei Wei Wang

Bibliographic record

VenueEncyclopedia of Industrial Biotechnology · 2010
Typeother
Languageen
FieldNeuroscience
TopicNeuroscience and Neural Engineering
Canadian institutionsWestern University
Fundersnot available
KeywordsMultielectrode arrayComputer scienceVisual phototransductionNanotechnologyMaterials scienceElectronicsMicroelectrodeElectrodeRetinaOpticsEngineeringChemistryElectrical engineering

Abstract

fetched live from OpenAlex

Abstract Biophotoreceptor arrays are hybrid electronic devices that utilize spectrally sensitive neuronal cells and biomolecules as the primary photon‐detecting element in a distributed network of light sensors. The patterned microelectrode arrays that interface with the biological material are constructed from readily available silicon‐based circuitry or, more recently, electrodes imprinted on flexible polymer substrates. From an engineer's perspective, these biological materials present new design opportunities for developing imaging systems that more closely emulate the signal detection and information processing structures found in nature. Several important attributes of natural vision include highly sensitive light receptors based on molecular phototransduction, a nonregular distribution of sensing elements on the imaging surface, and nonplanar image formation in the eye. The primate retina is one illustrative example of how phototransduction and neuronal interactions can lead to efficient imaging of dynamic three‐dimensional environments. The extraction and deposition of nerve cells and molecular proteins on microelectrode array platforms provide researchers with a means to observe the behavior of these distributed sensing systems. Organic and flexible polymer electronics represent a new technology that permit the creation of nonrigid photoreceptor arrays which replicate the curved imaging surfaces of single aperture and apposition compound eyes. A simple motion detection system is presented as an illustration of how photosensitive biomaterials and flexible printed electronics provide an alternative paradigm for developing new types of imaging systems. An important area where biomedical researchers can exploit engineered biophotoreceptor arrays is the fabrication of biocompatible artificial retinas and prosthetic devices for patients with severe visual impairment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.017
Threshold uncertainty score0.058

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0170.009

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.243
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes1
Has abstractyes

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