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Record W4246112699 · doi:10.1002/9780470054581.eib128

Biophotoreceptor Arrays

2010· other· en· W4246112699 on OpenAlexaff
George K. Knopf, Wei Wei Wang

Bibliographic record

VenueEncyclopedia of Industrial Biotechnology · 2010
Typeother
Languageen
FieldNeuroscience
TopicNeuroscience and Neural Engineering
Canadian institutionsWestern University
Fundersnot available
KeywordsMultielectrode arrayComputer scienceVisual phototransductionNanotechnologyMaterials scienceElectronicsMicroelectrodeElectrodeRetinaOpticsEngineeringChemistryElectrical engineering

Abstract

fetched live from OpenAlex

Abstract Biophotoreceptor arrays are hybrid electronic devices that utilize spectrally sensitive neuronal cells and biomolecules as the primary photon‐detecting element in a distributed network of light sensors. The patterned microelectrode arrays that interface with the biological material are constructed from readily available silicon‐based circuitry or, more recently, electrodes imprinted on flexible polymer substrates. From an engineer's perspective, these biological materials present new design opportunities for developing imaging systems that more closely emulate the signal detection and information processing structures found in nature. Several important attributes of natural vision include highly sensitive light receptors based on molecular phototransduction, a nonregular distribution of sensing elements on the imaging surface, and nonplanar image formation in the eye. The primate retina is one illustrative example of how phototransduction and neuronal interactions can lead to efficient imaging of dynamic three‐dimensional environments. The extraction and deposition of nerve cells and molecular proteins on microelectrode array platforms provide researchers with a means to observe the behavior of these distributed sensing systems. Organic and flexible polymer electronics represent a new technology that permit the creation of nonrigid photoreceptor arrays which replicate the curved imaging surfaces of single aperture and apposition compound eyes. A simple motion detection system is presented as an illustration of how photosensitive biomaterials and flexible printed electronics provide an alternative paradigm for developing new types of imaging systems. An important area where biomedical researchers can exploit engineered biophotoreceptor arrays is the fabrication of biocompatible artificial retinas and prosthetic devices for patients with severe visual impairment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.408
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.243
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes1
Has abstractyes

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