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Record W4246220398 · doi:10.1093/bioinformatics/btt046

A system for exact and approximate genetic linkage analysis of SNP data in large pedigrees

2013· article· en· W4246220398 on OpenAlexaffabout
Mark Silberstein, Omer Weissbrod, Lars Otten, Anna Tzemach, Andrei Anisenia, Oren Shtark, Dvir Tuberg, Eddie Galfrin, Irena Gannon, Adel Shalata, Zvi Borochowitz, Rina Dechter, E. A. Thompson, Dan Geiger

Bibliographic record

VenueBioinformatics · 2013
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic Associations and Epidemiology
Canadian institutionsUniversity of Ottawa
Fundersnot available
KeywordsPedigree chartLinkage (software)SNPComputer scienceGeneticsGenetic linkageGenetic dataComputational biologyBiologyData miningSingle-nucleotide polymorphismGenotypePopulationMedicineGene

Abstract

fetched live from OpenAlex

Vol. 29, No. 2, 2013, pp. 197–205 doi:10.1093/bioinformatics/bts658 The publishers regret that the author affiliations for this paper should appear as follows: Mark Silberstein1,2, Omer Weissbrod1,*, Lars Otten3, Anna Tzemach1, Andrei Anisenia1,4, Oren Shtark1, Dvir Tuberg1, Eddie Galfrin1, Irena Gannon1, Adel Shalata5,6,7, Zvi U. Borochowitz5,8, Rina Dechter3, Elizabeth Thompson9 and Dan Geiger1 1Department of Computer Science, Technion-Israel Institute of Technology, Haifa, Israel, 2Department of Computer Science, University of Texas at Austin, Austin, TX, USA, 3Donald Bren School of Information and Computer Sciences, UC Irvine, CA, USA, 4Department of Computer Science, University of Ottawa, Ottawa, Canada, 5The Simon Winter Institute for Human Genetics, Bnai-Zion Medical Center, Haifa, Israel, 6Research and Development Center, The Galilee Society, Shefa-Amr, Israel, 7Holy Family Hospital, Nazareth, Israel, 8The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa, Israel and 9Department of Statistics, University of Washington, Seattle, WA, USA

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.641
Threshold uncertainty score0.358

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.279
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2013
Admission routes2
Has abstractyes

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