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Record W4246269831 · doi:10.32920/ryerson.14663661

Optoacoustic imaging of gold nanorod based photothermal therapy

2021· preprint· en· W4246269831 on OpenAlexaff
Mehrnaz Tabibi

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldEngineering
TopicPhotoacoustic and Ultrasonic Imaging
Canadian institutionsToronto Metropolitan University
Fundersnot available
KeywordsNanorodPhotothermal therapyMaterials scienceImaging phantomIrradiationPhotothermal effectBiomedical engineeringOptoelectronicsLaserOpticsNanotechnologyMedicinePhysics

Abstract

fetched live from OpenAlex

Gold Nanorod Photothermal Therapy (GNR-PTT) is a minimally invasive technique and an alternative to surgery for destroying tumors while sparing normal tissues. Gold Nanorods (GNRs) with strong extinction peaks in the near infra-red (NIR) spectrum is a good candidate to convert light into thermal energy to destroy tumors. Opto-acoustic imaging (OAI) is a non-invasive method that detects time-resolved acoustic waves created by short pulses of NIR in tissue. It leads to a pressure rise in the irradiated volume. The question of whether OAI is a suitable candidate for temperature monitoring of GNR-PTT in the NIR spectrum was examined. In this thesis, for the first time, GNRs in a gel phantom was used to monitor the temperature during PTT with different laser powers and GNR concentrations. The imaging was performed by a commercial device IMAGIO, Seno, TX. The results show changes of the OA signal follow to temperature changes. The concentration of GNR and the power have a significant role in producing good results.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.213
Teacher spread0.203 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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