Platypnea-Orthodeoxia Syndrome With Atrial Septal Defect and Ectatic Aortic Root: A Case Report and Review of the Literature
Bibliographic record
Abstract
Platypnea-orthodeoxia syndrome (POS) is a rare and underdiagnosed disease characterized by dyspnea in the upright position (platypnea) with simultaneous hypoxemia (orthodeoxia) that is relieved by recumbency. The physiopathological mechanisms involved are mediated by intracardiac shunts, pulmonary arteriovenous shunts or ventilation/perfusion mismatch. When POS is caused by a cardiac pathology, there is an anatomical (interatrial communication) and a functional component (as a dilated aorta or pneumectomy) working together to cause a right to left shunt without a constant right to left pressure gradient. Diagnosis is suspected through pulse oximetry verifying orthodeoxia. Confirmation usually is made by transesophageal echocardiography with bubble study to visualize the shunt. Percutaneous closure of the shunt is effective in most cases of cardiac POS. We report a case of an 87-year-old woman with POS related to a patent foramen ovale and an ectatic aorta followed by a review of the literature. J Med Cases. 2016;7(2):54-57 doi: http://dx.doi.org/10.14740/jmc2414w
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".