4th International Phytocosmetics and Phytotherapy Congress (Guatemala - IPPC2016)
Bibliographic record
Abstract
Extracts of the tropical fern complex Phlebodium spp. (Polypodiaceae) common to Central American forests, have demonstrated beneficial properties for the skin attributed to the presence of numerous compounds with diverse pharmacological and cosmetic properties. Orally administered Phlebodium complex extracts may provide protection against the detrimental photoaging effects of sunlight and can help reduce the frequency and severity of polymorphous light eruption. It has also shown to be beneficial for the prevention and potential treatment of several aesthetically relevant conditions. The purpose of this review is to show the beneficial role of Phlebodium complex as an adjunct treatment for vitiligo, melasma, and post-inflammatory hyper-pigmentation and show the most important studies developed in Guatemala. Various extracts of Phlebodium complex applied topically or taken orally, have demonstrated several beneficial effects, such as antioxidant, photoprotector, immunomodulatory and antimutagenic. Modern studies have evaluated the efficacy of Phlebodium extracts as a photo-protective agent and for use in several photo-aggravated dermatologic disorders, such as polymorphous light eruption, other photo-dermatoses, vitiligo, melasma, psoriasis, atopic dermatitis, and more recently, in minimizing infections in high-performance athletes. It is these multiple mechanisms of action, in combination with a favorable side effect profile, which makes Phlebodium complex a promising adjunctive treatment for several dermatologic disorders, as well as application to the cosmetic industry. Aerial part has proven to exert antioxidant, photo-protective and immunomodulatory activities; extracts of fronds or rhizome are a natural mixture of phytochemicals endowed with powerful antioxidant properties, mainly due to the content of flavonoids, steroids and adenosine. Phlebodium fern frond and rhizome extracts block the deleterious effect of UV irradiation both in vivo and in vitro, showing potential as a natural photo-protectant and potential adjuvant to phototherapy of various skin diseases. Pre-clinical and clinical studies have demonstrated the immunomodulatory effect that can control vitiligo, atopic dermatitis and other chronic dermic diseases.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.126 | 0.039 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".