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Record W4247586306 · doi:10.1017/s0317167100052288

Amyotrophic Lateral Sclerosis

2000· article· fr· W4247586306 on OpenAlexvenueno aff

Bibliographic record

VenueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · 2000
Typearticle
Languagefr
FieldMedicine
TopicAmyotrophic Lateral Sclerosis Research
Canadian institutionsnot available
Fundersnot available
KeywordsAmyotrophic lateral sclerosisNeurosciencePhysical medicine and rehabilitationMedicineComputer sciencePsychologyPathologyDisease

Abstract

fetched live from OpenAlex

Patient 1 (Figure 1) is a 48-year-old female who presented with a three to four year history of fatigue and right leg cramps, which progressed to severe muscle spasms and difficulty walking.EMG suggested Amyotrophic lateral sclerosis (ALS).She has subsequently developed bilateral upper and lower extremity and truncal weakness, and some difficulty swallowing.Patient 2 (Figure 2) is a 31-year-old male who presented with right index finger weakness.This progressed over one month to involve the entire right arm, the neck, and the left arm.Physical examination also demonstrated truncal and lower extremity weakness, as well as mildly impaired speech and swallowing.Upper and lower motor neurons were affected, with no sensory involvement.EMG suggested ALS.ALS, the most common form of motor neuron disease, is a progressive neurodegenerative disorder of unknown etiology.Most cases are sporadic but a small percentage are inherited in an autosomal dominant fashion.Diagnosis is clinical, and based on El Escorial criteria, which include the presence of upper and lower motor neuron signs and the progression of abnormalities over at least six to 12 months after disease onset.No autonomic, sensory, or cognitive involvement should be present.Although the primary role of imaging is to exclude other

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.050
Threshold uncertainty score0.167

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0500.024

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.292
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2000
Admission routes1
Has abstractyes

Explore more

Same venueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques→Same topicAmyotrophic Lateral Sclerosis Research→French-language works237,207→