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Record W4248108714 · doi:10.7326/acpjc-2002-136-1-016

Omalizumab reduced inhaled corticosteroid use and exacerbations in childhood allergic asthma

2002· article· en· W4248108714 on OpenAlexaffabout
Bruce Mazer

Bibliographic record

VenueACP Journal Club · 2002
Typearticle
Languageen
FieldMedicine
TopicAsthma and respiratory diseases
Canadian institutionsChristie (Canada)
Fundersnot available
KeywordsOmalizumabMedicineImmunoglobulin EAsthmaAllergyAntibodyInternal medicineImmunology

Abstract

fetched live from OpenAlex

TherapeuticsJanuary 1, 2002Omalizumab reduced inhaled corticosteroid use and exacerbations in childhood allergic asthmaBruce Mazer, MD, Bruce Mazer, MDBruce Mazer, MDMeakins Christie Laboratories, Montreal, Quebec, Canada (B.M., B.M.)Meakins Christie Laboratories, Montreal, Quebec, Canada (B.M., B.M.)Search for more papers by this author, Bruce Mazer, MDMeakins Christie Laboratories, Montreal, Quebec, Canada (B.M., B.M.)Meakins Christie Laboratories, Montreal, Quebec, Canada (B.M., B.M.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/ACPJC-2002-136-1-016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareFacebookTwitterLinkedInRedditEmail Source CitationMilgrom H, Berger W, Nayak A, et al. Treatment of childhood asthma with anti-immunoglobulin E antibody (omalizumab). Pediatrics. 2001 Aug;108:e36. https://pubmed.ncbi.nlm.nih.gov/11483846References1 Busse W, Corren J, Lanier Q, et al. Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma. J Allergy Clin Immunol. 2001;108:184-90. Google Scholar2 Soler M, Matz J, Townley R, et al. The anti-IgE antibody omalizumab reduces exacerbations and steroid requirements in allergic asthmatics. Eur Respir J. 2001;18:254-61. Google Scholar3 Milgrom H, Fick RB, Jr., Su JQ, et al. Treatment of allergic asthma with monoclonal anti IgE antibody. N Engl J Med. 1999;341:1966-73. Google Scholar Author, Article, and Disclosure InformationAffiliations: Meakins Christie Laboratories, Montreal, Quebec, Canada (B.M., B.M.)Meakins Christie Laboratories, Montreal, Quebec, Canada (B.M., B.M.) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails January 1, 2002Volume 136, Issue 1Page: 16KeywordsAsthmaBody weightBronchodilatorsChildrenCorticosteroid therapyDustElectrocardiographyLungsMitesPediatricsPulmonary diseasesResearch laboratoriesRespiratory system proceduresSkin testsSubcutaneous injectionsSystemic diseasesThoraxUpper respiratory tract infections ePublished: 9 March 2020 Issue Published: January 1, 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.016
Threshold uncertainty score0.031

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0090.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.257
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2002
Admission routes2
Has abstractyes

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