Bibliographic record
Abstract
Drs Mulholland and Gardiner express concern about the Canadian Paediatric Society (CPS) position on the prevention of neonatal ophthalmia, which advocates for discontinuation of mandatory ocular prophylaxis (1). Whenever a preventive measure is recommended, the potential risks and benefits must be assessed carefully, as such measures are predominately directed at those who are healthy. The vast majority of neonates born in Canada are not at risk for ophthalmia neonatorum (ON). Hence prophylaxis must show very strong benefit and minimal risk within the context of care options to be acceptable. An important point that the authors do not mention is that in Canada at present, the only option for ocular prophylaxis is erythromycin ointment. Regarding the efficacy of ocular prophylaxis, Darling and McDonald concluded that while it appears that prophylaxis does reduce the risk of gonococcal ON (GON) and chlamydia ON (CON), all agents have significant failure rates (2). While these failure rates may have been acceptable in the pre-antibiotic era, when there was no option for treatment, today we have options that, based on the efficacy of screening and treatment, are expected to be more effective. Erythromycin failures with GON were demonstrated even in the era when gonococci were susceptible, and efficacy against CON is questionable (3–6). The evidence of benefit of erythromycin prophylaxis today is not strong.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.016 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.003 | 0.003 |
| Open science | 0.002 | 0.002 |
| Research integrity | 0.014 | 0.012 |
| Insufficient payload (model declined to judge) | 0.124 | 0.069 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".