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S112 Long-term safety and efficacy of ivacaftor in pediatric patients aged 2-5 years with cystic fibrosis and a cftr gating mutation

2016· article· en· W4249503169 on OpenAlexfundno aff

Bibliographic record

VenueThorax · 2016
Typearticle
Languageen
FieldMedicine
TopicCystic Fibrosis Research Advances
Canadian institutionsnot available
FundersFonds de Recherche du Québec - SantéGlaxoSmithKlineReseau canadien de recherche respiratoireAstraZenecaMcGill University Health CentrePfizer
KeywordsIvacaftorMedicineStock (firearms)Cystic fibrosisStock optionsClinical trialFamily medicineInternal medicineFinanceCystic fibrosis transmembrane conductance regulatorBusinessEngineering

Abstract

fetched live from OpenAlex

JC Davies has served on advisory boards, undertaken educational activities, and served as national/site principal investigator for trials, for which her institution has received funding from Vertex Pharmaceuticals Incorporated. S Robertson is an employee of Vertex Pharmaceuticals Incorporated and may own stock or stock options in that company. J Cooke is an employee of Vertex Pharmaceuticals Incorporated and may own stock or stock options in that company. M Higgins is an employee of Vertex Pharmaceuticals Incorporated and my own stock or stock options in that company. M Rosenfeld: has served as a national and site investigator for trials and as a consultant, for which her institution received funding from Vertex Pharmaceuticals Incorporated.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.059
Threshold uncertainty score0.269

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.286
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes1
Has abstractyes

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