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Record W4251544401 · doi:10.21203/rs.3.rs-408330/v1

Longitudinal Trajectories of Cognitive Function after Stroke: A Prospective Cohort Study

2021· preprint· en· W4251544401 on OpenAlexaboutno aff
Dongni Buvarp, Lena Rafsten, Tamar Abzhandadze, Katharina S. Sunnerhagen

Bibliographic record

VenueResearch Square · 2021
Typepreprint
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsnot available
FundersHealth and Medical Care Committee of the Regional Executive Board, Region Västra GötalandSTROKE-RiksförbundetHjärt-LungfondenStroke AssociationStiftelsen Promobilia
KeywordsCognitionMontreal Cognitive AssessmentStroke (engine)RehabilitationCognitive skillPhysical medicine and rehabilitationCohortPopulationNormativeLongitudinal studyPsychologyActivities of daily livingMedicinePhysical therapyGerontologyCognitive impairmentPsychiatryInternal medicine

Abstract

fetched live from OpenAlex

Abstract Background The study aimed to determine longitudinal trajectories of cognitive function during the first year after stroke. MethodsThe Montreal Cognitive Assessment (MoCA) was used to screen cognitive function at 36-48 hours, 3-months, and 12-months post-stroke. Individuals who shared similar trajectories were classified by applying the group-based trajectory models. ResultsData from 94 patients were included in the analysis. Three cognitive functioning groups were identified by the trajectory models: high (14 patients [15%]), medium (58 [62%]) and low (22 [23%]). For the high and medium groups, cognitive function improved at 12 months, but this did not occur in the low group. After age, sex and education matching to normative MoCA form the Swedish population, 52 patients (55%) were found to be cognitively impaired at baseline, and few patients had recovered at 12 months. The impact on memory differs between cognitive functioning groups, whereas the impact on activities of daily live was not different.ConclusionsPatients with the poorest cognitive function did not improve at one-year poststroke and were prone to severe memory problems. These findings may help to increase focus on long-term rehabilitation plans for those patients, and to more accurately assess their needs and difficulties experienced in daily living.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.022

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.400
Teacher spread0.358 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2021
Admission routes1
Has abstractyes

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