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Record W4253593779 · doi:10.32920/ryerson.14664081

Biomedical applications of photoacoustics for thermal therapy

2021· preprint· en· W4253593779 on OpenAlexaff
Robin F. Castelino

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldEngineering
TopicPhotoacoustic and Ultrasonic Imaging
Canadian institutionsToronto Metropolitan University
Fundersnot available
KeywordsImaging phantomPhotoacoustic imaging in biomedicineTransducerMaterials scienceBiomedical engineeringLaserGelatinWavelengthOpticsAcousticsOptoelectronicsMedicineChemistryPhysics

Abstract

fetched live from OpenAlex

This work demonstrates the feasibility of Photoacoustic tomography (PAT) and real-time photoacoustic (PA) monitoring using a single transducer prototype system to detect and/or monitor tumour growth using low absorbing targets embedded in turbid phantom and thermal lesions in tissue. A single transducer PA prototype system is build utilizing a laser system producing light in the near infra-red while untrasonic transducers detects the PA pressure waves generated. The ability to image tissue using PAT is initially demonstrated using gelatin phantoms with targets of similar optical properties to native and coagulated prostate tissue. Next, lesions in bovine muscle tissue and bovine liver are also imaged demonstrating the effectiveness of PAT tp detect lesions during thermal therapy (TT). Selective imaging is shown by varying the optical wavelength to preferentially absorb light and target specific structures which in turn produce high contrast after image reconstruction. Finally, the capability of using PA to monitor TT is explored by measuring the changes in the optical and mechanical properties of tissue equivalent albumen phantoms as a function of thermal dose on PA signals, thereby demonstrating the real time capability of this modality to monitor TT.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.246
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2021
Admission routes1
Has abstractyes

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