Childhood sexual trauma in women with interstitial cystitis/bladder pain syndrome: a case control study
Bibliographic record
Abstract
Background: The impact of early lifetime trauma on symptomseverity and quality of life of patients with interstitial cystitis/bladderpain syndrome (IC/BPS) has not been fully elucidated. Wewanted to determine and compare the prevalence and impact ofchildhood traumatic events, with an emphasis on childhood sexualabuse, on patient symptoms, quality of life and other biopsychosocialparameters.Methods: Subjects (female patients with IC/BPS and controls withoutIC/BPS) completed psychosocial phenotyping questionnaires,including a demographics/history form, and validated questionnairesfocused on presenting symptoms (IC symptom indices, pain),psychosocial parameters (depression, anxiety, pain catastrophizing,sexual functioning, social support) and quality of life. Participantsalso completed the Childhood Traumatic Events Scale.Results: Questionnaires were completed by 207 IC/BPS patientsand 117 controls matched for age, partner status and education. Itwas found that before 17 years of age, the IC/BPS cases reportedhigher prevalence of “raped or molested” compared to controls(24.0% vs. 14.7%; p = 0.047). Within the IC/BPS group, casesreporting previous sexual abuse endorsed greater sensory pain,depression and poorer physical quality of life at the present timecompared to IC cases without a sexual abuse history. In the controlsonly, those reporting previous sexual abuse endorsed more depression,anxiety, stress, social maladjustment poorer mental qualityof life in the present time. When the analysis was corrected forpotential multiple comparison error, none of the findings remainedsignificant in either the IC/BPS or control groups.Interpretation: Childhood traumatic events, in particular sexualabuse and extreme illness, are reported as more common in IC/BPS patients than controls. Early trauma, such as the occurrenceof sexual abuse, is associated with some differences in patientadjustment (e.g., pain, quality of life, depression) but this impactappears to be, at most, very modest.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".