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Record W4254197201 · doi:10.1038/sj.modpathol.3801041

Liver & Pancreas

2008· article· en· W4254197201 on OpenAlexaff
H-C Yang, L-J Ma, Yingting Zuo, Sebastian A. Potthoff, Paul Tennant, Rupert Abdalian, Farshid Siadat, E. Jenny Heathcote, Maha Guindi, Consuelo Macías Abraham, T-T Rosen, Z. Afshar-Ghotli, Shin-ichi Aishima, Yunosuke Nishihara, Ken Taguchi

Bibliographic record

VenueModern Pathology · 2008
Typearticle
Languageen
FieldMedicine
TopicLiver Disease Diagnosis and Treatment
Canadian institutionsUniversity Health NetworkUniversity of Toronto
Fundersnot available
KeywordsPancreasPathologyMedicineInternal medicine

Abstract

fetched live from OpenAlex

system. In addition, a subgroup of these patients were screened for antibody to major and minor histocompatibility antigens with solid phase assays using purified antigens and the Luminex technology. Results: Thirteen of fifteen (13/15) explants were found to be positive for C4d deposition indicating a humoral component of rejection. C4d deposition was also found to strongly correlate with the presence of vascular fibrinoid necrosis, but no other correlation with evaluated vascular changes could be noted. Nearly all cases demonstrated moderate or severe tubular atrophy, glomerulosclerosis, interstitial inflammation, and vascular intimal sclerosis. All recipients had detectable circulating antibodies against both major (HLA Class I and /or II) and/or Minor Histocompatibility Antigens. Notably, the antibodies present were donor specific in the majority of recipients tested.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.035
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.270
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2008
Admission routes1
Has abstractyes

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