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Record W4255167454 · doi:10.1093/bfgp/elu041

Fungal genomics

2014· editorial· en· W4255167454 on OpenAlexaff
Adrian Tsang

Bibliographic record

VenueBriefings in Functional Genomics · 2014
Typeeditorial
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPlant Pathogens and Fungal Diseases
Canadian institutionsConcordia University
Fundersnot available
KeywordsBiologyGenomicsComputational biologyEvolutionary biologyGeneticsGenomeGene

Abstract

fetched live from OpenAlex

Fungal genomicsFrom inconspicuous microorganisms to moulds to mushrooms, the biodiversity of filamentous fungi is enormous.They are the major decomposers of plant-derived biomass and play an essential role in biogeochemical cycling in the terrestrial biosphere.While edible mushrooms have been part of the human diet for over 2000 years, some filamentous fungi are the causative agents of animal and plant diseases.Filamentous fungi have been used as cell factories to produce antibiotics, therapeutics, enzymes and organic acids.The enzymes produced by them are used in food, feed, detergent, pulp and other industries.Since the publication of the genome of Phanerochaete chrysosporium [1], the first for filamentous fungi, over 400 filamentous fungal genomes have been sequenced or are being sequenced (http://gen omeonline.org).The genome-sequenced fungi fall into two broad groups, one with medical relevance [2] and the other comprising fungi with impact on biogeochemical cycling and biofuels development [3].Until now, over 75% of the genomes sequenced belong to four classes of the Fungal Kingdom: Agaricomycetes, Dithideomycetes, Eurotiomycetes and Sordariomycetes.To capture the biodiversity present in the Fungal Kingdom, the 1000 Fungal Genomes Project (www.1000.fungalgenome.org),initiated in 2011 in collaboration with the Joint Genome Institute of the U.S. Department of Energy, plans to sequence two species from every known family of the Fungal Kingdom.The completed and ongoing efforts in fungal genomes provide foundational information that will help researchers understand how fungi work in diverse ecologies.The articles in this special issue review features that are unique to filamentous fungi as unravelled by genomic approaches.The first article [4] addresses the approaches and resources available for post-genome sequencing research in filamentous fungi.Poorly assembled and characterized genomes make functional genomic analysis of many filamentous fungi challenging.For the hundreds of evolutionarily diverse genomes that

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Editorial · Consensus signal: none
Teacher disagreement score0.076
Threshold uncertainty score0.253

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0020.003
Science and technology studies0.0020.000
Scholarly communication0.0050.002
Open science0.0020.003
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0760.083

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.208
Teacher spread0.200 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2014
Admission routes1
Has abstractyes

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