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Record W4255196927 · doi:10.5206/uwomj.v89i2.10414

A Rare Case of Myocarditis Induced by Cannabis Use

2021· article· en· W4255196927 on OpenAlexaffvenue
Tony Jung, Brynn Charron

Bibliographic record

VenueUniversity of Western Ontario Medical Journal · 2021
Typearticle
Languageen
FieldMedicine
TopicCannabis and Cannabinoid Research
Canadian institutionsWestern University
Fundersnot available
KeywordsCannabisMyocarditisMedicineTetrahydrocannabinolEffects of cannabisAutopsyDepression (economics)Adverse effectPsychiatryInternal medicineCannabinoid

Abstract

fetched live from OpenAlex

Cannabis is one of the most commonly abused drugs in the world and there is a widespread misconception that cannabis is a safe drug without adverse effects. Tetrahydrocannabinol (THC) is one of the main chemicals of cannabis and considerable research suggests that cannabis and THC may have severe consequences on mental as well as physical health. However, the cardiovascular effects of cannabis are not well known. This article outlines the first reported case of pediatric death due to myocarditis induced by cannabis exposure. The subject is an 11-month-old male without any previous medical history that presented to the emergency department with central nervous system depression. The patient then went into cardiac arrest and died. Autopsy revealed myocarditis as the cause of death. Post-mortem blood analysis further revealed high concentrations of Δ-9-THC which is a metabolite of THC that can be detected for 24 hours after exposure. Considering that no other alternate causes of myocarditis have been confirmed, this raises cannabis exposure as the most likely cause. Although this is the first case of death from cannabis-induced myocarditis, there have been other cases wherein which cannabis exposure lead to myocarditis in young males. Altogether, these cases highlight the need for further investigation into the cardiovascular effects of cannabis and to consider cannabis in the diagnosis of myocarditis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.001
Science and technology studies0.0040.002
Scholarly communication0.0020.002
Open science0.0020.002
Research integrity0.0060.004
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.258
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes2
Has abstractyes

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Same venueUniversity of Western Ontario Medical JournalSame topicCannabis and Cannabinoid ResearchFrench-language works237,207