Syphilitic Hepatitis: An Uncommon Manifestation
Bibliographic record
Abstract
Syphilis is a systemic disease caused by the transmission through sexual contact of Treponema pallidum . It has a high incidence in men who have sex with other men, and is associated with human immunodeficiency virus (HIV) infection. The diagnosis depends on serological tests or confirmation of the spirochete in histological samples. The primary lesion courses after a latency period of 2 to 6 weeks, and the secondary disseminated phase, usually associated with mucocutaneous lesions and lymphadenopathy, may involve any organ. Symptomatic syphilitic hepatitis is a rare manifestation, the diagnosis of which is a challenge. It is characterized by a marked elevation of alkaline phosphatase, moderate elevation of transaminases, and no bilirubin changes. Histologically, portal inflammation and non-caseous granulomas predominate without associated necrosis. The case described is a rare manifestation of secondary syphilis, in the form of hepatitis in a sexually active HIV-infected patient with good response to the recommended benzathine penicillin treatment. J Med Cases. 2019;10(7):222-223 doi: https://doi.org/10.14740/jmc3254
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.005 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".