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Record W4255528582 · doi:10.1055/s-2007-976493

Human Metapneumovirus

2007· review· en· W4255528582 on OpenAlexaff
Céline Deffrasnes, Marie‐Ève Hamelin, Guy Boivin

Bibliographic record

VenueSeminars in Respiratory and Critical Care Medicine · 2007
Typereview
Languageen
FieldMedicine
TopicRespiratory viral infections research
Canadian institutionsUniversité Laval
Fundersnot available
KeywordsHuman metapneumovirusMedicineBronchiolitisMetapneumovirusPneumoniaRibavirinVirologyFastidious organismRespiratory tract infectionsImmunologyVirusLower respiratory tract infectionParamyxoviridaePneumovirusRespiratory tractRespiratory systemViral diseaseInternal medicineBiology

Abstract

fetched live from OpenAlex

Human metapneumovirus (hMPV) is a newly discovered paramyxovirus associated with upper and lower respiratory tract infections most commonly in young children, elderly subjects, and immunocompromised patients. hMPV can cause severe infections such as bronchiolitis and pneumonia and is responsible for 5 to 10% of hospitalizations of children suffering from acute respiratory tract infections. Such infections are indistinguishable from those caused by human respiratory syncytial virus. The first hMPV infection occurs during early childhood but reinfections are common throughout life, especially in older subjects. Molecular methods such as reverse transcriptase polymerase chain reaction (RT-PCR) are the preferred diagnostic modality due to fastidious growth in cell culture. Promising experimental models have been developed to better understand hMPV pathogenesis and to evaluate the potential effect of different therapeutic modalities. No commercial treatments are yet available for hMPV, although ribavirin has shown activity both in vitro and in animal models. Live attenuated vaccines produced by reverse genetics have also shown good efficacy in animals.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.006
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0060.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.181
GPT teacher head0.511
Teacher spread0.330 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations56
Published2007
Admission routes1
Has abstractyes

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