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Effects of nuts on glycemic control and coronary heart disease risk factors in type 2 diabetes

2010· article· en· W42682046 on OpenAlexaffabout
Cyril W.C. Kendall, Amin Esfahani, Tina Parker, Monica S. Banach, Sandra A. Mitchell, David J.A. Jenkins

Bibliographic record

VenueThe FASEB Journal · 2010
Typearticle
Languageen
FieldNursing
TopicNuts composition and effects
Canadian institutionsUniversity of TorontoSt. Michael's Hospital
Fundersnot available
KeywordsGlycemicMedicineNutType 2 diabetesDiabetes mellitusInternal medicineEndocrinology

Abstract

fetched live from OpenAlex

Background Nut consumption, including peanuts, has been associated with a reduced risk of coronary heart disease (CHD). More recently, interest has grown in the potential value of nuts in diets of individuals with diabetes. Objective To determine if tree nuts and peanuts improve glycemic control and CHD risk factors in type 2 diabetes. Methods 117 subjects with type 2 diabetes were randomized to a 3‐month parallel design study. Subjects were randomized to one of three treatments: 1) Test (Full Dose Nut Diet): 75g/d for 2,000kcal/d; 2) Test (Half Dose Nut Diet): half‐dose of nuts and half‐dose of control muffin; and 3) Control: whole wheat muffins matched with energy content of nut supplements. Fasting blood samples were collected at baseline and weeks 2, 4, 8, 10 and 12 for markers of glycemic control and CHD risk factors. Results Compared to the control, the full dose nut supplement significantly lowered HbA1c (P=0.039), total‐C (P=0.002), LDL‐C (P=0.007), total‐C:HDL‐C (P=0.015), and LDL‐C:HDL‐C (P=0.028). The half‐dose of nuts did not result in any significant improvements in glycemic control or blood lipids. Conclusions The addition of nuts to the diet improves glycemic control and reduces blood lipid CHD risk factors in type 2 diabetes. (Funded by Canada Research Chair Endowment; International Tree Nut Council Nutrition Research & Education Foundation; The Peanut Institute)

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.592
Threshold uncertainty score0.276

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.225
Teacher spread0.221 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes2
Has abstractyes

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