A fusion approach to improve accuracy and estimate uncertainty in cuffless blood pressure monitoring
Why this work is in the frame
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Bibliographic record
Abstract
A substantial barrier to the clinical adoption of cuffless blood pressure (BP) monitoring techniques is the lack of unified error standards and methods of estimating measurement uncertainty. This study proposes a fusion approach to improve accuracy and estimate prediction interval (PI) as a proxy for uncertainty for cuffless blood BP monitoring. BP was estimated during activities of daily living using three model architectures: nonlinear autoregressive models with exogenous inputs, feedforward neural network models, and pulse arrival time models. Multiple one-class support vector machine (OCSVM) models were trained to cluster data in terms of the percentage of outliers. New BP estimates were then assigned to a cluster using the OCSVMs hyperplanes, and the PIs were estimated using the BP error standard deviation associated with different clusters. The OCSVM was used to estimate the PI for the three BP models. The three BP estimations from the models were fused using the covariance intersection fusion algorithm, which improved BP and PI estimates in comparison with individual model precision by up to 24%. The employed model fusion shows promise in estimating BP and PI for potential clinical uses. The PI indicates that about 71%, 64%, and 29% of the data collected from sitting, standing, and walking can result in high-quality BP estimates. Our PI estimator offers an effective uncertainty metric to quantify the quality of BP estimates and can minimize the risk of false diagnosis.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it