MétaCan
Menu
Back to cohort
Record W4280581414 · doi:10.1016/j.leukres.2022.106858

Genetic changes during leukemic transformation to secondary acute myeloid leukemia from myeloproliferative neoplasms

2022· article· en· W4280581414 on OpenAlexafffund
Tae‐Hyung Kim, Jae-Sook Ahn, Meong Hi Son, Igor Novitzky‐Basso, Seong Yoon Yi, Seo-Yeon Ahn, Sung‐Hoon Jung, Deok‐Hwan Yang, Je‐Jung Lee, Seung Hyun Choi, Ja-Yeon Lee, Joon Ho Moon, Sang Kyun Sohn, Hyeoung‐Joon Kim, Zhaolei Zhang, Dennis Dong Hwan Kim

Bibliographic record

VenueLeukemia Research · 2022
Typearticle
Languageen
FieldMedicine
TopicMyeloproliferative Neoplasms: Diagnosis and Treatment
Canadian institutionsUniversity of TorontoPrincess Margaret Cancer Centre
FundersNational Research Foundation of KoreaMinistry of Health and WelfareMinistry of Science, ICT and Future PlanningNational Natural Science Foundation of ChinaNatural Sciences and Engineering Research Council of CanadaPrincess Margaret Cancer Foundation
KeywordsMyeloid leukemiaCancer researchMyeloidBiologyAlleleMutationMyeloproliferative DisordersGeneSpliceosomeMalignant transformationInternal medicineGeneticsOncologyImmunologyMedicineRNA splicing

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.422
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0020.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.322
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2022
Admission routes2
Has abstractno

Explore more

Same venueLeukemia ResearchSame topicMyeloproliferative Neoplasms: Diagnosis and TreatmentFrench-language works237,207