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Record W4281249692 · doi:10.1002/tbio.202100009

Optical spectroscopy and imaging in surgical management of cancer patients

2022· article· en· W4281249692 on OpenAlexafffund
Brian C. Wilson, Donovan Eu

Bibliographic record

VenueTranslational Biophotonics · 2022
Typearticle
Languageen
FieldMedicine
TopicOptical Imaging and Spectroscopy Techniques
Canadian institutionsPrincess Margaret Cancer CentreUniversity of TorontoUniversity Health Network
FundersCanadian Cancer Society Research InstituteTerry Fox Research Institute
KeywordsModalitiesMedicineMedical physicsBiophotonicsCancerRadiologyPathologyComputer scienceMaterials sciencePhotonicsInternal medicine

Abstract

fetched live from OpenAlex

Abstract Surgery is a pillar of cancer management, the general goal being complete removal of solid tumor tissue with minimal damage to normal tissue structure and function. Optical imaging and spectroscopy may contribute to this at several points in the procedural chain, including preoperative tumor localization and staging by biopsy, intra/perioperative identification and localization of tumor margins, detection of residual tumor tissue and tumor‐involved lymph nodes as well as critical normal tissue structures, and assessment of the viability of reconstructed tissues following tumor resection. The numerous optical modalities that can be implemented clinically are discussed, a few of which are already in clinical practice and many more are in clinical trials. These modalities utilize different light‐tissue interactions and technical approaches. The resulting biological information obtained, the current or potential clinical impact, limitations and potential future developments and roles are considered. This article is intended to inform the biophotonics community of the clinical needs and scientific/technical challenges and opportunities in photonics‐enabled surgical guidance and to guide potential surgical users on the potential advantages and limitations in this rapidly evolving landscape.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.044
Threshold uncertainty score0.318

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.306
Teacher spread0.298 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations11
Published2022
Admission routes2
Has abstractyes

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