Durable discontinuation of systemic therapy for chronic graft-<i>versus</i>-host disease: myth or reality?
Bibliographic record
Abstract
Definition off ST % off ST Setting Risk factors for longer time to discontinuation Chen 2022 6 684 12 months 24% at 5 years Multi-center Peripheral blood 32% at 10 years Myeloablative conditioning Moderate-severe GI cGvHD Lee symptom score Stewart 2004 7 751 Not stated 50% at 7 years Single center Peripheral blood Female donor to male HLA mismatch Multiple cGVHD sites Elevated serum bilirubin Perez 2008 8 171 Not stated 68% at 5 years Single center Acute GvHD Moderate-severe GI cGvHD Curtis 2017 9 227 6 months 27.7% at 5 years Qauternary center Cyclosporine prophylaxis Extensive skin sclerosis Lee 2018 10 250 9 months 32% at 5 years Single center Shorter time from HCT Oral cGvHD Skin cGvHD
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".