MétaCan
Menu
Back to cohort
Record W4281610032 · doi:10.1002/aur.2760

Early predictors of language skills at 3 years of age vary based on diagnostic outcome: A baby siblings research consortium study

2022· article· en· W4281610032 on OpenAlexaff
Meredith Pecukonis, Gregory S. Young, Jessica Brian, Tony Charman, Katarzyna Chawarska, Mayada Elsabbagh, Jana M. Iverson, Shafali Jeste, Rebecca Landa, Daniel S. Messinger, A. J. Schwichtenberg, Sara Jane Webb, Lonnie Zwaigenbaum, Helen Tager‐Flusberg

Bibliographic record

VenueAutism Research · 2022
Typearticle
Languageen
FieldNeuroscience
TopicAutism Spectrum Disorder Research
Canadian institutionsUniversity of AlbertaMcGill UniversityMontreal Neurological Institute and HospitalUniversity of Toronto
FundersNational Center for Advancing Translational SciencesNational Institutes of HealthNational Institute of Mental HealthAutism Science FoundationNational Institute on Deafness and Other Communication DisordersEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentAutism Speaks
KeywordsAutism spectrum disorderAutismDevelopmental psychologyPsychologyLanguage developmentLanguage delayNonverbal communicationGestureCognitionCognitive skillIntervention (counseling)Clinical psychologyPsychiatry

Abstract

fetched live from OpenAlex

While previous work has identified the early predictors of language skills in infants at elevated familial risk (ER) and low familial risk (LR) for autism spectrum disorder (ASD), no studies to date have explored whether these predictors vary based on diagnostic outcome of ASD or no ASD. The present study used a large, multisite dataset to examine associations between a set of commonly studied predictor variables (infant gesture abilities, fine motor skills, nonverbal cognition, and maternal education level), measured at 12 months, and language skills, measured at 3 years, across three diagnostic outcome groups-infants with ASD ("ASD"), ER infants without ASD ("ER-no ASD"), and LR infants without ASD ("LR-no ASD"). Findings revealed that the predictors of language skills differed across groups, as gesture abilities were positively associated with language skills in the ER-no ASD group but negatively associated with language skills in the ASD group. Furthermore, maternal education level was positively associated with language skills in the ASD and LR-no ASD groups only. Variability in these early predictors may help explain why language skills are heterogeneous across the autism spectrum, and, with further study, may help clinicians identify those in need of additional and/or specialized intervention services that support language development. LAY SUMMARY: The present study identified predictors of language skills in infants with and without autism spectrum disorder (ASD). Maternal education level and 12-month gesture abilities predicted 3-year language skills in infants with ASD. Measuring these predictors early in life may help identify infants and families in need of additional and/or specialized intervention services that support language development.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.015
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.161
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0100.015
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0030.006
Science and technology studies0.0010.002
Scholarly communication0.0000.000
Open science0.0030.004
Research integrity0.0000.003
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.079
GPT teacher head0.403
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations14
Published2022
Admission routes1
Has abstractyes

Explore more

Same venueAutism ResearchSame topicAutism Spectrum Disorder ResearchFrench-language works237,207