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Record W4281658853 · doi:10.1038/s41398-022-01963-5

Correction: Clinical utility of combinatorial pharmacogenomic testing in depression: A Canadian patient- and rater-blinded, randomized, controlled trial

2022· erratum· en· W4281658853 on OpenAlexaffabout
Arun K. Tiwari, Clement C. Zai, C. Anthony Altar, Julie‐Anne Tanner, Paige E. Davies, Paul Traxler, James Li, Elizabeth S. Cogan, Matthew Kucera, Ana Gugila, Nicole Braganza, Heather Emmerson, Gwyneth Zai, Daniel J. Müller, Robert D. Levitan, Stefan Kloiber, Zafiris J. Daskalakis, Benício N. Frey, James M. Bowen, Jean‐Éric Tarride, Richard Tytus, Ranjith Chandrasena, Nicholas Voudouris, Valerie H. Taylor, Raymond Tempier, Verinder Sharma, Akshya Vasudev, Peter Dzongowski, Lew Pliamm, Todd Greenspoon, Bryan Dechairo, James L. Kennedy

Bibliographic record

VenueTranslational Psychiatry · 2022
Typeerratum
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicPharmacogenetics and Drug Metabolism
Canadian institutionsHamilton Health SciencesParkwood InstituteUniversity of OttawaThornhill Medical (Canada)University of CalgaryImpactTed Rogers Centre for Heart ResearchWestern UniversityUniversity of TorontoMontfort HospitalUniversity Health NetworkCentre for Addiction and Mental HealthPrograms for Assessment of Technology in Health Research InstituteSt. Joseph’s Healthcare HamiltonMcMaster University
Fundersnot available
KeywordsRandomized controlled trialDepression (economics)MedicinePhysical therapyClinical trialDouble blindedPharmacogenomicsMedical physicsPsychologyPsychiatryAlternative medicineInternal medicinePlaceboPharmacologyPathology

Abstract

fetched live from OpenAlex

The original version of this article unfortunately contained mistakes. To ensure the accuracy of their article the authors would like to make the following corrections: Correction #1 Page 5, paragraph 1, line 5: Text currently reads “136”. This is incorrect and the authors are requesting to change it to “149”. Correction #2 Page 7, paragraph 4, line 17: Text currently reads “mild and moderately depressed patients”. This is incorrect and the authors are requesting to change it to: “patients with no or mild depression”. Correction #3 Supplementary Materials, Supplementary Table 2: The following Antipsychotic medications are incorrectly listed under Antidepressants: Olanzapine, Paliperidone, Perphenazine, Quetiapine, Risperidone, Thiothixene, Ziprasidone. The authors are requesting to update Supplementary Table 2 to include the above Antipsychotic medications in the Antipsychotic medication section of the table. The authors apologize for the errors. The original article has been corrected accordingly.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.018
metaresearch head score (Gemma)0.213
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.967
Threshold uncertainty score0.229

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0180.213
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0020.002
Science and technology studies0.0020.002
Scholarly communication0.0030.001
Open science0.0020.001
Research integrity0.0050.005
Insufficient payload (model declined to judge)0.0680.014

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.101
GPT teacher head0.424
Teacher spread0.323 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2022
Admission routes2
Has abstractyes

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