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Record W4283069023 · doi:10.1101/2022.06.16.496444

The phoenix hypothesis of speciation

2022· preprint· en· W4283069023 on OpenAlexafffund
Ryo Yamaguchi, Bryn Wiley, Sarah P. Otto

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2022
Typepreprint
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEvolution and Genetic Dynamics
Canadian institutionsUniversity of British Columbia
FundersJapan Society for the Promotion of ScienceNatural Sciences and Engineering Research Council of Canada
KeywordsAllopatric speciationReproductive isolationBiologyEvolutionary biologyExtinction (optical mineralogy)Genetic algorithmAdaptation (eye)PopulationIncipient speciationGenetic divergenceMutation rateEcologyGeneticsGenetic variationGenetic diversityGene flowGeneDemography

Abstract

fetched live from OpenAlex

Abstract Genetic divergence among allopatric populations builds reproductive isolation over time and is thought to be the major mechanism underlying the formation of new species. This process is accelerated when populations face a changing environment, but abrupt change also places populations at risk of extinction. Here we use simulations of Fisher’s geometric model with explicit population dynamics to explore the genetic changes that occur in the face of extreme environmental changes to which populations must adapt or go extinct. We show that evolutionary rescue leads to the fixation of mutations whose effects are larger on average and that these mutations are more likely to lead to reproductive isolation, compared with populations not at risk of extinction. We refer to the formation of new species from the ashes of populations in decline as the phoenix hypothesis of speciation. The phoenix hypothesis predicts more substantial hybrid fitness breakdown among populations surviving a higher extinction risk. The hypothesis was supported when many loci underlie adaptation. When, however, there was only a small number of potential rescue mutations, we found that mutations fixed in different populations were more likely to be identical, with parallel changes reducing isolation. With a limited genomic potential for adaptation, we find support for a modified version of the phoenix hypothesis where reproductive isolation builds fastest in populations subject to an intermediate extinction risk. While processes driving extinction lead to the loss of lineages with deep evolutionary histories, they may also generate new taxa, albeit taxa with minimal genetic differences.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.210
Teacher spread0.200 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2022
Admission routes2
Has abstractyes

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