The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Abstract
The upcoming 5th edition of the World Health Organization (WHO) Classification of Haematolymphoid Tumours is part of an effort to hierarchically catalogue human cancers arising in various organ systems within a single relational database. This paper summarizes the new WHO classification scheme for myeloid and histiocytic/dendritic neoplasms and provides an overview of the principles and rationale underpinning changes from the prior edition. The definition and diagnosis of disease types continues to be based on multiple clinicopathologic parameters, but with refinement of diagnostic criteria and emphasis on therapeutically and/or prognostically actionable biomarkers. While a genetic basis for defining diseases is sought where possible, the classification strives to keep practical worldwide applicability in perspective. The result is an enhanced, contemporary, evidence-based classification of myeloid and histiocytic/dendritic neoplasms, rooted in molecular biology and an organizational structure that permits future scalability as new discoveries continue to inexorably inform future editions.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
The record
- Venue
- Leukemia
- Topic
- Acute Myeloid Leukemia Research
- Field
- Medicine
- Canadian institutions
- Université de MontréalHôpital Maisonneuve-RosemontHospital for Sick Children
- Funders
- Sahlgrenska AkademinNational Cancer InstituteDepartment of Laboratory Medicine and Pathology, University of WashingtonSchool of Medicine, Indiana UniversityUniversity of Texas MD Anderson Cancer CenterUniversitätsklinikum JenaHospital for Sick ChildrenUniversity of California, San DiegoNational University Cancer Institute, SingaporeMedizinischen Hochschule HannoverUniversité de MontréalCentre National de la Recherche ScientifiqueSchool of Medicine, Stanford UniversityFudan UniversityInstitut Gustave-RoussySahlgrenska UniversitetssjukhusetVrije Universiteit AmsterdamUniversity of OxfordWellcome TrustUniversity of SouthamptonUniversity of AlabamaTexas Children's HospitalAmsterdam University Medical CentersMoffitt Cancer CenterInstitut National de la Santé et de la Recherche MédicaleUniversity of WashingtonMemorial Sloan-Kettering Cancer CenterKnight Cancer Institute, Oregon Health and Science UniversityUniversität UlmUniversity of Texas Southwestern Medical CenterImperial College LondonChildren's Hospital Los AngelesNational Institute for Health and Care ResearchAssistance publique-Hôpitaux de ParisMassachusetts General HospitalUniversité Paris-SaclayUniversity of Alabama at BirminghamNationwide Children's HospitalCincinnati Children's Hospital Medical CenterCentre International de Recherche sur le CancerGöteborgs UniversitetRadboud UniversiteitRadboud Universitair Medisch CentrumUniversità degli Studi di MilanoUniversity of Pennsylvania
- Keywords
- HistiocyteMyeloidDiseaseHematologic NeoplasmsMedicineComputational biologyComputer scienceBiologyPathologyImmunologyCancerInternal medicine
- Has abstract in OpenAlex
- yes