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Record W4283312488 · doi:10.1126/science.abm0151

Diverse aging rates in ectothermic tetrapods provide insights for the evolution of aging and longevity

2022· article· en· W4283312488 on OpenAlexaff
Beth A. Reinke, Hugo Cayuela, Fredric J. Janzen, Jean‐François Lemaître, Jean‐Michel Gaillard, A. Michelle Lawing, John B. Iverson, Ditte G. Christiansen, Í‪ñigo Martínez-Solano, Gregorio Sánchez‐Montes, Jorge Gutiérrez‐Rodríguez, Francis L. Rose, Nicola J. Nelson, Susan N. Keall, Alain J. Crivellì, Theodoros Nazirides, Annegret Grimm‐Seyfarth, Klaus Henle, Emiliano Mori, Gaëtan Guiller, Rebecca Newcomb Homan, Anthony Olivier, Erin Muths, Blake R. Hossack, Xavier Bonnet, David S. Pilliod, Marieke Lettink, Tony Whitaker, Benedikt R. Schmidt, M. Gardner, Marc Cheylan, Françoise Poitevin, Ana Golubović, Ljiljana Tomović, Dragan Arsovski, Richard A. Griffiths, Jan W. Arntzen, Jean‐Pierre Baron, Jean‐François Le Galliard, Thomas N. Tully, Luca Luiselli, Massimo Capula, Lorenzo Rugiero, Rebecca McCaffery, Lisa A. Eby, Venetia Briggs‐Gonzalez, Frank J. Mazzotti, David Pearson, Brad A. Lambert, David M. Green, Nathalie Jreidini, Claudio Angelini, Graham H. Pyke, Jean‐Marc Thirion, Pierre Joly, Jean‐Paul Léna, Anton D. Tucker, Col Limpus, Pauline Priol, Aurélien Besnard, Pauline Bernard, Kristin Stanford, Richard B. King, Justin M. Garwood, Jaime Bosch, Franco L. Souza, Jaime Bertoluci, Shirley Famelli, Kurt Grossenbacher, Omar Lenzi, Kathleen Matthews, Sylvain Boitaud, Deanna H. Olson, Tim S. Jessop, Graeme R. Gillespie, Jean Clobert, Murielle Richard, Andrés Valenzuela‐Sánchez, Gary M. Fellers, Patrick M. Kleeman, Brian J. Halstead, Evan H. Campbell Grant, Phillip G. Byrne, THIERRY FRÉTEY, Bernard Le Garff, Pauline Levionnois, John C. Maerz, Julian Pichenot, Kurtuluş Olgun, Nazan Üzüm, Aziz Avcı, Claude Miaud, Johan Elmberg, Gregory P. Brown, Richard Shine, Nathan F. Bendik, Lisa O’Donnell, Courtney L. Davis, Michael J. Lannoo, Rochelle M. Stiles, Robert M. Cox, Aaron M. Reedy, Daniel A. Warner, Éric Bonnaire, Kristine L. Grayson, Roberto Ramos-Targarona, Eyüp Başkale, David Muñóz, John Measey, F. André de Villiers, Will Selman, Victor Ronget, Anne M. Bronikowski, David A. Miller

Bibliographic record

VenueScience · 2022
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicAnimal Behavior and Reproduction
Canadian institutionsMcGill University
FundersNational Institute on AgingUniversity of CanberraU.S. Geological SurveyColorado Parks and WildlifeBundesamt für UmweltNational Science FoundationNational Institutes of HealthSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
KeywordsEctothermLongevityBiologyLife history theoryEvolutionary biologyContext (archaeology)Life historyHealthy agingEcologyZoologyGerontologyPaleontologyGenetics

Abstract

fetched live from OpenAlex

Comparative studies of mortality in the wild are necessary to understand the evolution of aging; yet, ectothermic tetrapods are underrepresented in this comparative landscape, despite their suitability for testing evolutionary hypotheses. We present a study of aging rates and longevity across wild tetrapod ectotherms, using data from 107 populations (77 species) of nonavian reptiles and amphibians. We test hypotheses of how thermoregulatory mode, environmental temperature, protective phenotypes, and pace of life history contribute to demographic aging. Controlling for phylogeny and body size, ectotherms display a higher diversity of aging rates compared with endotherms and include phylogenetically widespread evidence of negligible aging. Protective phenotypes and life-history strategies further explain macroevolutionary patterns of aging. Analyzing ectothermic tetrapods in a comparative context enhances our understanding of the evolution of aging.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.262
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations107
Published2022
Admission routes1
Has abstractyes

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