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Record W4283364198 · doi:10.1111/aor.14349

The use of digital image correlation for measurement of strain fields in a novel wireless intraspinal microstimulation interface

2022· article· en· W4283364198 on OpenAlexaff
Omar Tawakol, Vivian K. Mushahwar, Philip R. Troyk

Bibliographic record

VenueArtificial Organs · 2022
Typearticle
Languageen
FieldMedicine
TopicSpinal Cord Injury Research
Canadian institutionsWomen and Children’s Health Research InstituteUniversity of Alberta
FundersIllinois Institute of Technology
KeywordsMicrostimulationDigital image correlationBiomedical engineeringSpinal cord injurySpinal cordImplantStrain (injury)Materials scienceMedicineSurgeryAnatomy

Abstract

fetched live from OpenAlex

BACKGROUND: Intraspinal microstimulation (ISMS) has emerged as a promising neuromodulation technique for restoring standing and overground walking in individuals with spinal cord injury. Current and emerging ISMS implant designs connect the electrodes to the stimulator through lead wires that cross the dura mater. To reduce possible complications associated with transdural leads such as tethering and leakage of cerebrospinal fluid, we aim to develop a wireless, fully intradural ISMS implant based on our prior work in the cortex with the Wireless Floating Microelectrode Array (WFMA). Although we have extensive data about WFMA cortical stability, its mechanical and electrical stability in the spinal cord remains unknown. One of the quantifiable metrics to assess long-term implant stability is mechanical strain. OBJECTIVE: The aim of the current work is to develop a method to assess implant stability by measuring strain fields in a surrogate of the human spinal cord. METHODS: A physical model of the spinal cord was studied using an electromechanical testing apparatus, simulating typical spinal cord motion. Strain fields were digitally analyzed using an optical method known as digital image correlation (DIC). RESULTS: Displacement and strain were visualized using contour plots. The strain values in the vicinity of each WFMA device were significantly different from the strain values in the same locations in the control surrogate spinal cord. CONCLUSION: The results demonstrate that DIC can be used for in-vitro screening of intraspinal implants. Accurate optical strain measurements will enable researchers to optimize implant design over a wide range of motion conditions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.138
GPT teacher head0.364
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2022
Admission routes1
Has abstractyes

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