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Record W4283587489 · doi:10.14740/ijcp483

<i>Moraxella osloensis</i> Bacteremia and Pneumonia in a Seventeen-Year-Old Patient

2022· article· en· W4283587489 on OpenAlexvenueno aff
Holden Richards, Christina Lancioni, Michael J. Jones

Bibliographic record

VenueInternational Journal of Clinical Pediatrics · 2022
Typearticle
Languageen
FieldMedicine
TopicPneumonia and Respiratory Infections
Canadian institutionsnot available
Fundersnot available
KeywordsMoraxella catarrhalisMedicineBacteremiaPneumoniaMoraxellaAntibioticsBlood cultureIntensive care medicineInternal medicineMicrobiologyStreptococcus pneumoniaeBacteriaBiology

Abstract

fetched live from OpenAlex

Moraxella osloensis ( M . osloensis ) is a rare cause of bacteremia and pneumonia in pediatric patients. The published case reports of M. osloensis bacteremia are limited. Among children, there are only seven cases of invasive disease from M. osloensis identified, and specific treatment guidelines are not available. Our case adds to the limited literature on this rare bacterium and highlights the need to better define antimicrobial resistance patterns. Here we report a case of a 17-year-old previously healthy female admitted with M. osloensis bacteremia and pneumonia. The patient initially presented with clinical and radiographic findings consistent with community-acquired pneumonia and was sent home after an emergency department (ED) visit with oral antibiotic treatment. She was advised to return for admission after the blood culture obtained in the ED reported growth and was noted to have persistent symptoms despite antibiotic adherence. Treatment with ceftriaxone for 3 days intravenously followed by 7 days of oral cefdinir resulted in rapid clinical improvement and resolution of her infection. Due to its sparse prevalence in the literature, there is currently no standard antibiotic regimen for treatment of invasive infections with M. osloensis ; a variety of therapies ranging from 7 to 14 days in duration have been successfully employed. While Moraxella species (e.g., Moraxella catarrhalis ( M . catarrhalis )) are typically ?-lactamase producing, reports regarding ?-lactamase production by M . osloensis have been inconsistent. M . osloensis is a rare cause of invasive infection in adolescents. Given limited published data regarding antibiotic sensitivities of this specific organism, microbiologic sensitivities should be obtained if possible and response to therapy should be closely monitored. Int J Clin Pediatr. 2022;11(2):56-59 doi: https://doi.org/10.14740/ijcp483

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.174
Threshold uncertainty score0.454

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.357
Teacher spread0.330 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2022
Admission routes1
Has abstractyes

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