MétaCan
Menu
Back to cohort
Record W4284691137 · doi:10.1002/cyto.a.24670

<scp>flowCut:</scp> An R package for automated removal of outlier events and flagging of files based on time versus fluorescence analysis

2022· article· en· W4284691137 on OpenAlexafffund
Justin Meskas, Daniel Yokosawa, Sherrie Wang, Gabriela C. Segat, Ryan R. Brinkman

Bibliographic record

VenueCytometry Part A · 2022
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicSingle-cell and spatial transcriptomics
Canadian institutionsUniversity of British ColumbiaTerry Fox Research Institute
FundersNational Institute of General Medical SciencesNational Institute of Allergy and Infectious DiseasesCanadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada
KeywordsFlaggingComputer scienceOutlierAnomaly detectionSpurious relationshipR packageData miningArtificial intelligenceCartographyMachine learning

Abstract

fetched live from OpenAlex

Technical artifacts such as clogging that occur during the data acquisition process of flow cytometry data can cause spurious events and fluorescence intensity shifting that impact the quality of the data and its analysis results. These events should be identified and potentially removed before being passed to the next stage of analysis. flowCut, an R package, automatically detects anomaly events in flow cytometry experiments and flags files for potential review. Its results are on par with manual analysis and it outperforms existing automated approaches.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.022
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Software · Consensus signal: Software
Teacher disagreement score0.115
Threshold uncertainty score0.384

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.022
Meta-epidemiology (narrow)0.0040.002
Meta-epidemiology (broad)0.0030.003
Bibliometrics0.0040.002
Science and technology studies0.0010.001
Scholarly communication0.0040.003
Open science0.0030.003
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.1150.062

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.264
Teacher spread0.246 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreSoftware

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations42
Published2022
Admission routes2
Has abstractyes

Explore more

Same venueCytometry Part ASame topicSingle-cell and spatial transcriptomicsFrench-language works237,207