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Record W4285089722 · doi:10.53730/ijhs.v6ns6.10589

Preparation and preformualation estimation method of floating microsphere of ofloxacin

2022· article· en· W4285089722 on OpenAlexaff
Pravin G. Dhone, P. K. Sinha, Jitendra Mehta, Annapurna Sahoo

Bibliographic record

VenueInternational Journal of Health Sciences · 2022
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicDrug Solubulity and Delivery Systems
Canadian institutionsSKiN Health
Fundersnot available
KeywordsOfloxacinEthyl celluloseMicrosphereEmulsionDissolutionChromatographyBioavailabilityPulmonary surfactantSolventPolymerChemistryDiffusionDrug deliveryNuclear chemistryMaterials scienceChemical engineeringPharmacologyOrganic chemistryCiprofloxacin

Abstract

fetched live from OpenAlex

Floating drug delivery systems are mainly expected to remain buoyant in gastric contents and consequently to enhance the bioavailability of drugs Microsphere is loaded with a drug in their outer polymer shells was prepared by a novel emulsion-solvent diffusion method. It is floated continuously over the surface of acidic dissolution media containing the surfactant for invitro time 12 hours. Floating microspheres of ofloxacin were prepared by novel o/w emulsion solvent evaporation technique using Ethyl cellulose polymers order to retain drug in body for longer period of time. Ofloxacin has short half-life of 9 hrs. So we prepared a microsphere for increasing their activity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.364
Threshold uncertainty score0.192

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.135
GPT teacher head0.539
Teacher spread0.404 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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