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Record W4285089833 · doi:10.3389/fnsyn.2022.952564

Editorial: Regulation of AMPA Receptors, From the Genetic to the Functional Level

2022· editorial· en· W4285089833 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueFrontiers in Synaptic Neuroscience · 2022
Typeeditorial
Languageen
FieldNeuroscience
TopicNeuroscience and Neuropharmacology Research
Canadian institutionsDouglas Mental Health University InstituteDouglas CollegeMcGill University
Fundersnot available
KeywordsAMPA receptorNeurosciencePsychologyReceptorCognitive scienceComputer scienceBiologyGlutamate receptorGenetics

Abstract

fetched live from OpenAlex

AMPA receptors (AMPARs) are widely distributed in the central and peripheral nervous systems. They are mainly located in postsynaptic cells, but can also be found in pre-synaptic sites and glia processes. Upon glutamate stimulation, the postsynaptic AMPARs mediate the fast excitatory synaptic transmission which can be changed in an activity dependent manner and might involve a minority of Ca2+ permeable AMPARs. This Research Topic describes several new mechanisms that regulate AMPAR trafficking and plasticity; in addition to give novel insight to the function of AMPAR in the hypothalamus.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.016
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.122
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.016
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.003
Science and technology studies0.0010.002
Scholarly communication0.0000.000
Open science0.0050.002
Research integrity0.0000.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.301
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it