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Record W4285288617 · doi:10.37590/able.v42.abs33

A Picture is Worth 1000 Words: Using Pictorial Expression Data in Bioinformatics Assignments

2022· article· en· W4285288617 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueAdvances in Biology Laboratory Education · 2022
Typearticle
Languageen
FieldComputer Science
TopicMachine Learning and Data Classification
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsExpression (computer science)Computer scienceBioinformaticsComputational biologyData miningArtificial intelligenceBiologyProgramming language

Abstract

fetched live from OpenAlex

When learning bioinformatics, students are often given an unknown sequence and are required to perform a BLAST search to determine gene identity and % identity shared with genes in other species. The goal is usually for students to speculate the role of this unknown gene within their organism. We have found that access to visual information about expression patterns is very useful especially for non-experts like our students. Researchers from the University of Toronto developed the ePlant browsers that summarize expression data from thousands of experiments first in Arabidopsis (Winter et al. 2007) and now from a diverse array of plant species (as well as mice and humans). In this workshop we will use this online tool to explore expression of several genes in terms of tissue and subcellular specificity, developmental regulation, different physiological conditions and natural variation in different sub-species. It is also possible to look at a specific plant tissue or condition and find genes expressed within this tissue or condition. Expression data for any specific gene is linked with many other useful genomic tools. This tool could be used as a part of a genetics, developmental biology, cell biology, physiology or ecology lab.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.876
Threshold uncertainty score0.481

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.002
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.350
Teacher spread0.331 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it