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Record W4286493252 · doi:10.21203/rs.3.rs-1799255/v1

Occupational exposure to rare earth elements in mechanic workshops

2022· preprint· en· W4286493252 on OpenAlexaff
Marco Trifuoggi, Maria Rita Aiani, Giovanni Pagano, Paolo Mascagni, Luigi Borea, Serkan Tez, Rahime Oral, Marco Guida, Giovanni Libralato, Antonella Giarra, Maria Toscanesi, Pasquale Ranieri, Alessandra Marano, Francesco Gianpaolo, Elisa Galbiati, Simona Mariani, Maria Grazia Cucco, Philippe J. Thomas

Bibliographic record

VenueResearch Square · 2022
Typepreprint
Languageen
FieldEnvironmental Science
TopicRecycling and Waste Management Techniques
Canadian institutionsEnvironment and Climate Change Canada
FundersEuropean Commission
KeywordsRare earthOccupational exposureEnvironmental scienceEarth scienceGeologyEnvironmental healthMedicine

Abstract

fetched live from OpenAlex

Abstract Rare earth elements (REEs) such as cerium and lanthanum are utilized in oil refining and as catalytic additives in the production of diesel fuel aimed at optimizing fuel combustion. Background reports from animal studies demonstrated several REE-associated adverse effects, some of which following REE inhalation of diesel exhaust particulate. This study was aimed at evaluating the occupational exposure to REEs in diesel exhaust among two groups of mechanic workers; the first group involving 20 workers from artisanal workshops lacking exhaust abatement devices in Avellino province (Italy) and the second treatment group encompassing 82 workers (controls) from two industrial industrial-shaped workshops in Como (Italy) equipped with exhaust abatement devices. The evaluated endpoints in the two donor groups were: a) urine concentrations of 1-hydroxypyrene (1-OHP), as an indicator of exposure to polycyclic aromatic hydrocarbons (PAHs); b) urine REE concentrations, and c) REE concentrations in scalp hair. The results showed significantly higher urine 1-OHP concentrations in the first treatment group vs. controls (0.28 ± 0.07 mg/L vs. 0.12 ± 0.35 mg/L) (p<0.05), along with significantly higher frequency of smokers in these workers cases vs. controls (47.6% vs. 11.1%;) (p<0.05), and significantly higher urine REE concentrations in the same cases vs. controls (0.14 ± 0.04 mg/L vs. 0.07 ± 0.04 mg/L; ) (p<0.001). REE concentrations in scalp hair were not significantly different between the two donor groups suggesting that REEs might not be sequestered to hair during detoxification pathways.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.062
GPT teacher head0.387
Teacher spread0.325 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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