Effect of benzathine penicillin combined with ceftriaxone on the results of rapid plasma reagin circle card test/toluidine red unheated serum test in the treatment of early syphilis: a meta-analysis
Bibliographic record
Abstract
摘要： 【摘要】 目的 系统评价苄星青霉素联合头孢曲松治疗早期梅毒对血清快速血浆反应素环状卡片试验/甲苯胺红不加热血清试验（RPR/TRUST）转阴率的疗效。方法 检索PubMed、Web of science、Embase、Cochrane、中国知网、万方、维普数据库中关于苄星青霉素联合头孢曲松治疗早期梅毒的病例对照研究。使用Newcastle-Ottawa量表（NOS）评估纳入研究文献的质量，使用RevMan5.3软件分析患者RPR/TRUST转阴率。结果 共纳入14个病例对照研究1 160例梅毒患者，联合组585例，单用组575例。结果显示，联合组血清RPR/TRUST转阴率明显高于单用组［OR = 3.70，95% CI（2.71，5.06），P < 0.001］。按随访时间进行亚组分析，联合治疗组在治疗后3个月［OR = 3.68，95% CI（2.26，5.98），P < 0.001］、6个月［OR = 3.11，95% CI（2.26，4.27），P < 0.001］及12个月时［OR = 4.35，95% CI（2.81，6.73），P < 0.001］RPR/TRUST转阴率均高于单用组。结论 与苄星青霉素相比，苄星青霉素联合头孢曲松治疗早期梅毒能更有效地促进血清RPR/TRUST转阴。
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.009 | 0.016 |
| Meta-epidemiology (narrow) | 0.003 | 0.002 |
| Meta-epidemiology (broad) | 0.016 | 0.042 |
| Bibliometrics | 0.002 | 0.003 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.003 | 0.002 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.003 | 0.004 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".