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Record W4292998648 · doi:10.54097/hset.v8i.1121

Effects of Antipsychotic Drugs and Antimanic Drugs on Bipolar Disorder

2022· article· en· W4292998648 on OpenAlexaff
Weichu Chiu, Jie Geng, Qinglang Liao

Bibliographic record

VenueHighlights in Science Engineering and Technology · 2022
Typearticle
Languageen
FieldMedicine
TopicBipolar Disorder and Treatment
Canadian institutionsEarl Haig Secondary School
Fundersnot available
KeywordsBipolar disorderMoodTreatment of bipolar disorderLithium (medication)AntipsychoticPsychiatrySchizophrenia (object-oriented programming)ManiaPsychologyDepression (economics)DrugMedicineBipolar I disorderMood stabilizer

Abstract

fetched live from OpenAlex

The main incidence of Bipolar is concentrated in teenagers, and the fatality rate is as high as 11% and even exceeds that of depression. There are currently 3 mainstream drug treatments, mood stabilizers, epilepsy drugs, and antipsychotics. Mood stabilizers, also known as antimanic drugs, are now the most mainstream treatment centered around lithium. Numerous studies show that mood stabilizers have a very obvious effect on bipolar. It can not only relieve the manic state but also work on the patients in a depressed state. Antipsychotic drugs, also known as strong tranquilizers, are mainly used in schizophrenia, and bipolar disorder, they are mainly used to stabilize manic states but do not work on depression. However, these methods have their limitations. The development of future treatments should take into account the biological and psychological mechanisms of the disease. This article briefly introduces the therapeutic effects of different drugs on BD from clinical data and mechanisms.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.003
GPT teacher head0.212
Teacher spread0.209 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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