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Record W4293569136 · doi:10.53730/ijhs.v6ns6.12062

Detection of respiratory viruses in clinical samples

2022· article· en· W4293569136 on OpenAlexaff
Shubham Yadav, Vaishnav Wagh, Sakshi Pajai, Anto Simon M. Joseph, Ravindran Jaganathan, Durba Banerjee

Bibliographic record

VenueInternational Journal of Health Sciences · 2022
Typearticle
Languageen
FieldMedicine
TopicRespiratory viral infections research
Canadian institutionsRoyal College of Physicians and Surgeons of Canada
Fundersnot available
KeywordsGenomeDNA sequencingBiologyViral infectionRespiratory systemVirologyComputational biologyVirusGeneGenetics

Abstract

fetched live from OpenAlex

Respiratory viral infections accounts for more than 4.25 million fatalities each year, making them the third most common cause of death worldwide. Although the majority of acute respiratory infections are assumed to be caused by viruses, the exact cause is often unknown. Comprehensive mapping of viral genomic sequencing is done, which also shows a significant degree of viral heterogeneity that contributes to the early diagnosis of respiratory illness. The development of next-generation sequencing (NGS), particularly for the detection of unidentified respiratory viruses, has revolutionized the field of novel viral genome detection.This review focusses on different models of sequencing techniques available for novel viral genome detection. Although there are still major technical and ethical issues in using this technologies for clinical detection, this technology has great promise for the future as a way to better understand respiratory viruses and make diagnoses that are more precise.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.006
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0040.002
Science and technology studies0.0010.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0030.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.332
GPT teacher head0.559
Teacher spread0.227 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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