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Record W4294405937 · doi:10.7759/cureus.28730

Diagnosis: Fundamental Principles and Methods

2022· review· en· W4294405937 on OpenAlexaff
Martin Gale

Bibliographic record

VenueCureus · 2022
Typereview
Languageen
FieldMedicine
TopicClinical Reasoning and Diagnostic Skills
Canadian institutionsIvanhoe Energy (Canada)
Fundersnot available
KeywordsMedicineMedical diagnosisTerminologyProcess (computing)Health careHarmRisk analysis (engineering)Management scienceIntensive care medicineComputer sciencePathology

Abstract

fetched live from OpenAlex

Problem-solving is an essential human endeavor. It involves problem definition, followed by solution design, solution implementation, and, finally, review. Healthcare is a prime and often successful example of problem-solving. In medical terminology, the problem definition is termed the diagnosis, the solution design is called the treatment plan, and the solution itself is the provision of treatment. The case review is used to assess the efficacy of the solution. This process is sequential and consequential. Obviously, if a problem's definition is absent or incorrect, then an appropriate solution cannot be designed or implemented. Unfortunately, missed or incorrect diagnoses are not uncommon in healthcare and can cause considerable harm and economic cost. Minimizing these diagnostic errors would confer great benefits to patients, clinicians, and healthcare organizations. Understanding the nature of diagnosis and why it can be so difficult are some of the first steps in reducing these diagnostic errors. One issue is that diagnosis may seem to be more of an art than a science when the exact mechanisms of diagnosis are often not clearly described. Clinicians typically learn their diagnostic craft by mimicry of their mentors over years of hard experience. This absence of a clear method not only makes diagnosis difficult to do well it also makes diagnosis difficult to teach well. The purpose of this paper is to try to better articulate the fundamental principles and methods of diagnosis and to make diagnosis more intellectually understandable, and so more teachable, and more achievable by clinicians.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.013
metaresearch head score (Gemma)0.025
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.013
Threshold uncertainty score0.070

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0130.025
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0090.005
Science and technology studies0.0010.013
Scholarly communication0.0060.006
Open science0.0050.004
Research integrity0.0050.007
Insufficient payload (model declined to judge)0.0060.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.227
GPT teacher head0.510
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2022
Admission routes1
Has abstractyes

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