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Record W4294792824 · doi:10.1503/cmaj.220645

Pre-exposure prophylaxis for HIV: effective and underused

2022· review· en· W4294792824 on OpenAlexaffvenue
Amanda Hempel, Mia J. Biondi, Jean‐Guy Baril, Darrell H. S. Tan

Bibliographic record

VenueCanadian Medical Association Journal · 2022
Typereview
Languageen
FieldMedicine
TopicHIV/AIDS Research and Interventions
Canadian institutionsToronto Liver CentreYork UniversityUniversity Health NetworkUniversity of TorontoCentre Hospitalier de l’Université de MontréalSt. Michael's Hospital
FundersGilead Sciences
KeywordsPre-exposure prophylaxisHuman immunodeficiency virus (HIV)MedicineAgency (philosophy)Public healthIncidence (geometry)Treatment as preventionEnvironmental healthFamily medicineIntensive care medicineMen who have sex with menAntiretroviral therapyViral loadNursing

Abstract

fetched live from OpenAlex

KEY POINTS Incidence of HIV has been rising in Canada. The Public Health Agency of Canada estimated 2242 new HIV infections in 2018, which highlights the need for comprehensive prevention strategies. [1][1] Pre-exposure prophylaxis (PrEP) is an important means of preventing acquisition of HIV;

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.005
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0020.002
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.348
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2022
Admission routes2
Has abstractyes

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