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Record W4296157818 · doi:10.1101/2022.09.14.507986

Age-related complexity of the resting state MEG signals: a multiscale entropy analysis

2022· preprint· en· W4296157818 on OpenAlexaff
Armin Makani, Amir Akhavan, Farhad Shahbazi, Mohammad Noruzi, Marzieh Zare

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2022
Typepreprint
Languageen
FieldNeuroscience
TopicEEG and Brain-Computer Interfaces
Canadian institutionsMontreal General Hospital
Fundersnot available
KeywordsSample entropyResting state fMRIMagnetoencephalographyPsychologyFluid intelligenceCorrelationApproximate entropyCognitionBrain agingEntropy (arrow of time)RhythmNeuroscienceMathematicsPattern recognition (psychology)Cognitive psychologyElectroencephalographyInternal medicineMedicinePhysicsWorking memory

Abstract

fetched live from OpenAlex

Abstract The effects of aging on the brain can be studied by examining the changes in complexity of brain signals and fluid cognitive abilities. This paper is a relatively large-scale study in which the complexity of the resting-state MEG (rsMEG) signal was investigated in 602 healthy participants (298 females and 304 males) aged 18 to 87. In order to quantify the brain signals’ complexity, the multiscale entropy is applied. This study investigates the relationship between age and fluid intelligence with brain complexity and the variations of the complexity asymmetry between the left-right brain hemispheres across the life span. In the analysis of the brain signals, the gender difference was considered. The results showed that the complexity of rsMEG decreases across the lifespan. However, the complexity difference between the left-right brain hemispheres positively correlates with age. Furthermore, the results demonstrated that fluid intelligence and age have a positive correlation. Finally, the frequency analysis revealed a significant increase in the relative power of low and high gamma rhythms in females compared to males in all age groups.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.261
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2022
Admission routes1
Has abstractyes

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