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Record W4298214910 · doi:10.17615/rwwd-6217

International consensus guidelines for the diagnosis and management of food protein–induced enterocolitis syndrome: Executive summary—Workgroup Report of the Adverse Reactions to Foods Committee, American Academy of Allergy, Asthma & Immunology

2020· article· en· W4298214910 on OpenAlexfundno aff
Marisa Conte, Jennifer R. Lightdale, Yitzhak Katz, Sean McGhee, Hwang, Carla M. Davis, A. Wesley Burks, Matthew Greenhawt, Antonella Cianferoni, Hugh A. Sampson, Katrina J. Allen, Ichiro Nomura, Fallon Schultz, P. Turner, Brittany Hofmeister, George Ν. Konstantinou, Sami L. Bahna, Sally Noone, M. Cecilia Berin, Stacey Katherine Noel, Amity Westcott-Chavez, Alessandro Fiocchi, Robert A. Wood, Jean‐Christoph Caubet, Marion Groetch, Mirna Chehade, Antonella Muraro, Sami Mehr, Dan Atkins, Ashis V. Barad, Stefano Miceli Sopo, Cecilia Thompson, Kate Grimshaw, Stephanie A. Leonard, Anna Nowak‐Węgrzyn, Terri Brown Whitehorn, Scott H. Sicherer, Jonathan M. Spergel, R. Gupta, Carina Venter

Bibliographic record

VenueUNC Libraries · 2020
Typearticle
Languageen
FieldMedicine
TopicFood Allergy and Anaphylaxis Research
Canadian institutionsnot available
FundersNational Institute of Allergy and Infectious DiseasesMedical Research CouncilRegeneron PharmaceuticalsMylanNational Institutes of HealthNorgineHôpitaux Universitaires de GenèveNational Institute for Health and Care ResearchNational Peanut BoardFood Allergy Research and EducationAstellas PharmaPublic Health EnglandNational Institute for Health and Care ExcellenceIcahn School of Medicine at Mount SinaiAimmune TherapeuticsAmerican Partnership for Eosinophilic DisordersJohns Hopkins UniversityGenentechValeant Pharmaceuticals InternationalMead Johnson NutritionImperial College LondonDanoneAgency for Healthcare Research and QualitySanofi
KeywordsWorkgroupExecutive summaryFood allergyMedicineImmunologyAllergyAsthmaExecutive committeeEnterocolitisIntensive care medicineFamily medicineInternal medicineBiologyManagementBiotechnology

Abstract

fetched live from OpenAlex

Food protein-induced enterocolitis (FPIES) is a non-IgE cell- mediated food allergy that can be severe and lead to shock. Despite the potential seriousness of reactions, awareness of FPIES is low; high-quality studies providing insight into the pathophysiology, diagnosis, and management are lacking; and clinical outcomes are poorly established. This consensus document is the result of work done by an international workgroup convened through the Adverse Reactions to Foods Committee of the American Academy of Allergy, Asthma & Immunology and the International FPIES Association advocacy group. These are the first international evidence-based guidelines to improve the diagnosis and management of patients with FPIES. Research on prevalence, pathophysiology, diagnostic markers, and future treatments is necessary to improve the care of patients with FPIES. These guidelines will be updated periodically as more evidence becomes available.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.032
metaresearch head score (Gemma)0.064
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.032
Threshold uncertainty score0.170

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0320.064
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0040.006
Bibliometrics0.0100.006
Science and technology studies0.0020.002
Scholarly communication0.0040.003
Open science0.0090.003
Research integrity0.0100.012
Insufficient payload (model declined to judge)0.0080.010

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.081
GPT teacher head0.340
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations115
Published2020
Admission routes1
Has abstractyes

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Same venueUNC LibrariesSame topicFood Allergy and Anaphylaxis ResearchFrench-language works237,207