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Canine narcolepsy

2016· article· en· W4302358481 on OpenAlexaboutno aff
Deborah Eileen Menezes Baliellas, Josy Carolina Covan Pontes, Eduardo Fernandes Bondan

Bibliographic record

VenueClínica Veterinária · 2016
Typearticle
Languageen
FieldNeuroscience
TopicNeuroscience of respiration and sleep
Canadian institutionsnot available
Fundersnot available
KeywordsNarcolepsyCataplexyExcessive daytime sleepinessSleep paralysisMedicinePenetranceSleep (system call)Sleep disorderPsychologyNeuroscienceNeurologyPsychiatryInsomniaGeneGeneticsBiologyPhenotype

Abstract

fetched live from OpenAlex

Canine narcolepsy is a neurological disorder that affects the appearance and organization of sleep. It is characterized by excessive daytime sleepiness, cataplexy and hypnagogic hallucinations. In Doberman and Labrador breeds, narcolepsy is transmitted hereditarily by the canarc-1 recessive gene, which has complete penetrance and causes a mutation in the receptor for hypocretin-2, a neuropeptide that prevents entry into REM sleep by activating specific neurons. Diagnosis can be achieved by observing the symptoms. Cataplexy is a key factor for diagnosis of narcolepsy and must be carefully distinguished from other neurological diseases and reversible paralytic disorders. Treatment is palliative and based on the administration of stimulants of the central nervous system (CNS) and tricyclic antidepressants.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.035

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0100.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.066
GPT teacher head0.305
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2016
Admission routes1
Has abstractyes

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