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Record W4304184366 · doi:10.3390/sym14102051

Activation-Inhibition Coordination in Neuron, Brain, and Behavior Sequencing/Organization: Implications for Laterality and Lateralization

2022· article· en· W4304184366 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueSymmetry · 2022
Typearticle
Languageen
FieldNeuroscience
TopicNeuroscience, Education and Cognitive Function
Canadian institutionsYork University
Fundersnot available
KeywordsLateralization of brain functionNeurosciencePsychologyInhibitory postsynaptic potentialMechanism (biology)LateralityCognitive psychologyPhysics

Abstract

fetched live from OpenAlex

Activation-inhibition coordination is considered a dynamic process that functions as a common mechanism in the synchronization and functioning of neurons, brain, behavior, and their sequencing/organization, including over these different scales. The concept has broad applicability, for example, in applications to maladaptivity/atypicality. Young developed the hypothesis to help explain the efficacy of right-hand reaching to grasp in 1-month-olds, a study that implicated that the left hemisphere is specialized for activation-inhibition coordination. This underlying left-hemisphere function, noted to characterize the left hemisphere right from birth, can explain equally its language and fine motor skills, for example. The right hemisphere appears specialized for less complex inhibitory skills, such as outright damping/inhibition. The hypotheses related to inhibition and hemispheric specialization that appear in the literature typically refer to right hemisphere skills in these regards. The research to present also refers to excitation/inhibition balance/ratio in synaptic function, but not to coordination in the sense described here. Furthermore, it refers to the inhibitory function widely in neuronal networks. The paper presents a comprehensive literature review, framing the research in terms of the proposed concept. Further, the paper presents a broad model of activation-inhibition coordination that can help better understand neuron, brain, and behavior, generally, and left hemisphere specialization, specifically.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.793
Threshold uncertainty score0.508

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.292
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it