Obstructive Lung Disease Is About More Than Just Airways: Blood Supply Matters
Bibliographic record
Abstract
Within their small air sacs, our lungs exchange oxygen (O2) from the air for the carbon dioxide (CO2) produced by our bodies. In these air spaces, O2 moves into small blood vessels while CO2 moves from the blood out into the air. Lung diseases can impair airflow and reduce the number of blood vessels in the lungs, making it harder to take in O2 and eliminate CO2. These changes to the lungs contribute to symptoms like breathlessness. The relationship between airflow and blood flow in our lungs is called V/Q, where V is for ventilation—the movement of air—and Q is for perfusion—blood flow to the lungs. While people with healthy lungs have good a good match between V and Q, those with certain lung diseases often have poor V/Q matching. In this article, we describe the origins of V/Q mismatch and its impact on lung function.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.007 |
| Scholarly communication | 0.004 | 0.004 |
| Open science | 0.000 | 0.002 |
| Research integrity | 0.002 | 0.004 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".